Mahana IBS, The validated digital therapeutic for gut-directed CBT

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Provide a Clinically Validated, digital CBT Treatment for IBS

IBS-trained therapists are hard to find and access. That’s why we’ve developed a validated regulatory cleared digital therapeutic that delivers gut-directed cognitive behavioural therapy for IBS. 63% of patients treated with Mahana IBS in a clinical trial reported a clinically meaningful improvement in IBS symptom severity and saw durable effects for up to a year after their 90 day use.1,2

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Sign up to receive your free welcome pack:

  • How to use Mahana IBS in clinical practice with clinical evidence, FAQs and patient journey outlined
  • Updates on Mahana IBS progress and new data in the UK
  • An activation code for Healthcare professionals to demo the Mahana IBS programme

Regulatory Cleared, Clinically Validated and No Known Side Effects

The efficacy and safety of Mahana IBS was demonstrated in the  ACTIB trial of 558 adult patients with refractory IBS. Mahana helped nearly 2 in 3 people in a clinical trial.1,2

  • Mahana IBS was cleared as a class II device by the FDA3 and has gained UKCA and CE Mark after FDA
  • CBT allows patients to influence brain-gut communication in order to reduce the severity of IBS symptoms
  • Patients showed clinically and statistically significant improvements in IBS-SSS and WSAS with Mahana IBS added to TAU vs TAU alone
  • 63% of patients reported a clinically meaningful reduction in the severity of their IBS at the end of treatment with durable effects seen up to 1 year after the 90-day use

Clinically Significant and Durable Effectiveness

Provide patients with a regulatory-cleared, evidence-based digital therapy, to reduce symptom severity.

Mahana + TAU vs TAU graphMahana + TAU vs TAU graph

Getting Started is Simple

Healthcare Professionals in the UK can now access Mahana IBS for patients. Register your interest to receive more information on how we are working with the NHS and healthcare teams and to provide Mahana IBS for their patients. 

Mahana provider stepsHow to Prescribe

What is CBT and How Does it Help IBS?

Mahana’s cognitive behavioural therapy is gut-directed psychotherapy (GDP) that improves IBS symptom severity by targeting the cognitive factors known to drive symptoms. CBT is the most rigorously tested psychological treatment for IBS.

Image of Mahana 4 IBS on a cellphone screen

CBT is a safe, effective solution that works for all types of IBS (D, C & M).

Mahana enables you to empower all IBS patients with a treatment that has no known side effects.

The gut-brain axis is a contributing component to IBS symptomatology.

The gut-brain axis is a bidirectional communication system that links intestinal functions with the emotional and cognitive centers of the brain.

Join leading healthcare professionals who understand the importance of using innovative, validated digital therapeutic treatments to improve patient outcomes.

We Make Explaining Mahana IBS Easy

Explaining to patients the benefits of using Mahana IBS is fast and simple.

Explaining to patients the benefits of using Mahana IBS is fast and simple.

We have a variety of patient information leaflets, posters, videos to explain the benefits of Mahana IBS and also comprehensive clinical resources for HCPs.

CBT Model

Mahana IBS gut directed CBT helps patients develop skills in 10 key areas over the course of the 90 day programme to reduce severity of symptoms.

Relaxation; manage emotions; reduce unhelpful thoughts; improve eating patterns; reduce stress
Mahana IBS treatment cycle

Digital Health Tool Adoption Rate is Growing

Patients have more information at their fingertips than ever before. That’s why it’s imperative for physicians to anticipate and understand consumer health trends.

Mahana IBS is the first and only FDA cleared digital IBS treatment. With Mahana IBS, physicians can be confident they are prescribing an efficacious and safe digital health treatment

In 2021, the number of people using digital therapeutics is expected to reach 44 million worldwide. Almost double the number of users in 2020.4

Mahana IBS Advisors

We're working with leaders in gastroenterology to ensure patient and healthcare professionals have the tools they need for IBS treatment.

Hazel Everitt, PhD, FRCGP

Hazel Everitt, Ph.D, FRCGP

University of Southampton, GP & Professor of Primary Care Research

Emeran Mayer, M.D.

Emeran Mayer, M.D.

Director, G. Oppenheimer Center for Neurobiology of Stress and Resilience (CNSR)

Jasmine Zia, M.D.

Jasmine Zia, M.D.

Swedish Medical Center, Gastroenterologist

Rona Moss-Morris, Ph.D

Rona Moss-Morris, Ph.D

King's College London, Head of Psychology Department, Institute of Psychiatry, Psychology & Neuroscience

Women holding hands

Frequently Asked Questions

How effective is Mahana IBS?
  1. Mahana Therapeutics & ACTIB Trial, data on file. *clinically meaningful improvement defined as a > 50 point change in IBS-SSS from baseline
  2. Everitt HA et al. Gut. 2019 Sep;68(9):1613-1623.
  3. Food and Drug Administration. Device Classification Under Section 513(f)(2)(De Novo). 2020.
  4. Juniper Research. DIGITAL THERAPEUTICS & WELLNESS: DISRUPTION, INNOVATION OPPORTUNITIES & MARKET SIZE 2020-2025. 2020.
See Mahana IBS Clinician Information